Hookish enough?

Ok, I'm sure there are plenty of people out there who've whined about the writing process, and I'm not going to pretend I haven't. And this is my latest concern: I wonder if my story has enough of a hook. That's the important word, I guess, in the fiction biz: hook. I think what I wrote is something that women are going to be able to relate to, but it's not earth-shattering. So if there's no fancy hook, is a potential book doomed? Perhaps what I wrote is not hookish enough for the PIC (Publishing Industrial Complex). But I won't know until I polish my query letter and send it out. Then after 50 or so rejections, I will know, and will have to go back to the drawing (writing) board.